性别:男
个人主页://www.liufengsysu.cn
职称: 副教授
电子邮件: [email protected]
导师类型: 博士生导师
学历: 博士
学科方向
071010-生物化学与分子生物学
0860-生物与医药

 

研究方向

1. 新型蛋白质互作筛选工具的开发及其在衰老生物学中的应用;

2.   核内无膜亚细胞器的结构与功能分析。

 

个人经历

2019至今  成人直播APP   副教授

2015-2019 成人直播APP “百人计划”  讲师 

2011-2014 美国加州大学旧金山分校(UCSF)  博士后

2005-2011 北京大学成人直播APP  理学博士

2001-2005 成人直播APP  理学学士

 

讲授课程

成人直播APP 必修课《生物化学 I》(广东省一流本科课程;成人直播APP 一流本科课程)

成人直播APP 研究生必修课《学术规范与论文写作》

成人直播APP 研究生必修课《高级生物化学》

成人直播APP 强基班荣誉课程《生物化学和分子生物学讨论课》
成人直播APP 专业选修课《蛋白质与蛋白质组学》

 

学术成就

刘峰 副教授,博士生导师,成人直播APP “百人计划”引进人才,广东省杰出青年基金获得者。北京大学生物化学与分子生物学博士,美国加州大学旧金山分校(UCSF)博士后。现任成人直播APP 抗衰老研究中心副主任,生物化学系副主任,生化教研室主任,中国老年学和老年医学学会抗衰老分会委员,广东省生物化学与分子生物学学会理事。广东省一流本科(线下)课程“生物化学I”课程负责人。长期致力于蛋白质相互作用及信号转导研究,尤其关注衰老相关蛋白、细胞核内无膜细胞器相关蛋白的大规模筛选与功能机制研究。曾在Nature Cell Biology(入选F1000)、Cell Research(封面文章)、Nature Neuroscience、Neuron、Cell Reports、Molecular Psychiatry(入选F1000)、PNAS等杂志发表论文。曾获强生亚洲优秀论文奖和北京大学优秀博士论文奖。

 

论文专著

冯然, 刘峰, 吴苏, 李若菲, 松阳洲*. 蛋白质相互作用技术——功能基因组学研究利器. 中国科学: 生命科学, 2024 年, 第 54 卷, 第 9 期, 1603 - 1613 页.

Ran Feng#, Feng Liu#*, Ruofei Li, ZhifenZhou, Zhuoheng Lin, Song Lin, Shengcheng Deng, Yingying Li, Baoting Nong, YingXia, Zhiyi Li, Xiaoqin Zhong, Shuhan Yang, Gang Wan, Wenbin Ma, Su Wu* and Zhou Songyang*. The Rapid Proximity Labeling System PhastID identifies ATP6AP1 as an unconventional GEF for Rheb. Cell Research. (Cover Article) 2024. Mar 6. doi: 10.1038/s41422-024-00938-z.

Bohong Chen#, Tianyu Ge#, Meiqi Jian, Liutao Chen, Zhengwen Fang, Zibin He, Chengjing Huang, Yan An, Shanshan Yin, Yuanyan Xiong, JingKai Zhang, Ruofei Li, Miaoman Ye, Yubing Li, Feng Liu, Wenbin Ma, Zhou Songyang. Transmembrane nuclease NUMEN/ENDOD1 regulates DNA repair pathway choice at the nuclear periphery. Nature Cell Biology. 2023 Jun 15. doi: 10.1038/s41556-023-01165-1. 

Aging Biomarker Consortium;..., Feng Liu#, et al. Biomarkers of aging. Science China Life Sciences.(Cover Article) 2023 Apr 11. doi: 10.1007/s11427-023-2305-0. 

Jingwen Wang#, Jiahui Liu#, Miaoman Ye, Feng Liu, Su Wu, Junjiu Huang and Guang Shi*. Ddx56 maintains proliferation of mouse embryonic stem cells via ribosome assembly and interaction with the Oct4/Sox2 complex. Stem Cell Research & Therapy. 2020:11(314).

Su Wu#*, Siyao Xu#,Ruofei Li, Kecheng Li, Xiaoqin Zhong, Yingying Li, Zhifen Zhou, Yi Liu, Ran Feng, Jianfei Zheng, Zhou Songyang*Feng Liu*. mTORC1-Rps15 Axis Contributes to the Mechanisms Underlying Global Translation Reduction During Senescence of Mouse Embryonic Fibroblasts. Frontiers in Cell and Developmental Biology. 11 December 2019. //doi.org/10.3389/fcell.2019.00337. (IF: 5.2)

Jianxi Zhu, Mingyang Xu, Yi Liu, Lisha Zhuang, Kejun Ying, Feng Liu, Dan Liu, Wenbin Ma*, Zhou Songyang*. Phosphorylation of PLIN3 by AMPK promotes dispersion of lipid droplets during starvation. Protein & Cell. 2018, Nov 14. doi: 10.1007/s13238-018-0593-9.

Yumei Liao#, Xiaoji Zhuang#, Xiaojie Huang, Yinghui Peng, Xuanyue Ma, Zhi-Xing Huang, Feng Liu, Junyu Xu, Ying Wang, Wei-Min Chen*, Wen-Cai Ye*, Lei Shi*. A Bivalent Securinine Compound SN3-L6 Induces Neuronal Differentiation via Translational Upregulation of Neurogenic Transcription Factors. Frontiers in Pharmacology. 2018; Apr 5;9:290.

Yi Liu#, Feng Liu#*, Yizhao Cao, Huimin Xu, Yangxiu Wu, Su Wu, Dan Liu, Yong Zhao, Zhou Songyang*, Wenbin Ma*. Shwachman-Diamond Syndrome Protein SBDS Maintains Human Telomeres by Regulating Telomerase Recruitment. Cell Reports. 2018;22:1849-1860. (IF: 8.2)

Huan Yang#, Su Wu#, Ran Feng, Junjiu Huang, Lixiang Liu, Feng Liu*, Yuqing Chen*. Vitamin C plus hydrogel facilitates bone marrow stromal cell-mediated endometrium regeneration in rats. Stem Cell Research & Therapy. 2017:8(267). (IF: 4.2)

Sophie Laguesse, Nadege Morisot, Jung Hoon Shin, Feng Liu, Martin F. Adrover, Samuel A. Sakhai, Marcelo F. Lopez, Khanhky Phamluong, William C. Griffin III, Howard C. Becker, Kevin J. Bender, Veronica A. Alvarez, Dorit Ron*. Prosapip1-Dependent Synaptic Adaptations in the Nucleus Accumbens Drive Alcohol Intake, Seeking, and Reward. Neuron. 2017;96(1):145-159. (IF:14.0)

Feng Liu, Xuyang Feng, Wenbin Ma*. Analysis of Telomere Proteins by Chromatin Immunoprecipitation (ChIP). Methods in Molecular Biology. 2017;1587:205-214.

Feng Liu, Sophie Laguesse, Remi Legastelois, Nadege Morisot, Sami Ben Hamida, Dorit Ron*. mTORC1-dependent Translation of Collapsin Response Mediator Protein-2 Drives Neuroadaptations Underlying Excessive Alcohol Drinking Behaviors. Molecular Psychiatry. 2017;22:89-101.(IF: 13.2)

Emmanuel Darcq, Vincent Warnault, Khanhky Phamluong, Gabriel M Besserer, Feng Liu, Dorit Ron*. MicroRNA-30a-5p in the prefrontal cortex controls the transition from moderate to excessive alcohol consumption. Molecular Psychiatry. 2015;20(10):1219-31.(IF: 13.2)

Segev Barak, Feng Liu, Sami Ben Hamida, Quinn V Yowell, Jeremie Neasta, Viktor Kharazia, Patricia H Janak, Dorit Ron*. Disruption of alcohol-related memories by mTORC1 inhibition prevents relapse. Nature Neuroscience. 2013;16(8):1111-7.(IF: 17.8)

Feng Wang, Weiwei Xia, Feng Liu, Ji Li, Gang Wang, Jun Gu*. Interferon regulator factor 1/retinoic inducible gene I (IRF1/RIG-I) axismediates 25- hydroxycholesterol- induced interleukin-8 production in atherosclerosis. Cardiovascular Research.2012;93(1):190-9.(IF: 5.8)

Feng Liu#, Su Wu#, Hongwei Ren, Jun Gu*. Klotho suppresses RIG-I-mediated senescence-associated inflammation. Nature Cell Biology. 2011;13(3):254-62.(IF: 20.0)

Feng Liu, Jun Gu*. Retinoic acid inducible gene-I, more than a virus sensor. Protein & Cell. 2011;2(5):351-7.(IF: 5.3)

Lijuan Xu#, Nengming Xiao#, Feng Liu, Hongwei Ren, Jun Gu*. Inhibition of RIG-I and MDA5-dependentantiviral response by gC1qR at mitochondria. Proceedings of the National Academyof Sciences of the United States of America. 2009;106(5):1530-5.(IF: 9.6)

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